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Actress Katherine Heigl was the first celebrity to openly smoke an e-cig on television, prompting host David Letterman to claim the device was remarkable

Respiratory Issues Although nicotine itself is not the direct cause of respiratory diseases, its consumption through smoking exposes the lungs to thousands of harmful chemicals, including tar and carbon monoxide

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(Photo by Douglas Sacha/Getty Images) Cigarette consumption in Indiana dropped 40% during the first three months of a long-sought tax increase, according to the Indiana Department of Health